The warfarin dosing calculator tells you how to alter the warfarin dosage to keep the INR in your desired range. † For patients on triple therapy (e.g. warfarin, aspirin, clopidogrel), it might be reasonable to target a lower INR of 2-2.5 and use a PPI for duration of triple therapy Your dose may need to be changed several times in order to find out what works best for you. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take warfarin in larger or smaller amounts or for longer than your doctor tells you to. Take warfarin at the same time every day, with or without food. Medscape - Deep vein thrombosis, pulmonary embolism, recurrent myocardial infarction-specific dosing for Coumadin, Jantoven (warfarin), frequency-based adverse effects, comprehensive. Several studies have confirmed that 5mg initiation achieves therapeutic anticoagulation as rapidly as 10mg initiation but with a lower frequency of supra-therapeutic INRs. Welcome to WarfarinDosing.org, a free Web site to help doctors and other clinicians begin warfarin therapy by estimating the therapeutic dose in patients new to warfarin. This site is supported by the Barnes-Jewish Hospital at Washington University Medical Center, the NIH, and donations. Recent studies confirmed the importance of initiating warfarin therapy with lower doses (eg 5mg) as opposed to older protocols which advocated higher initial dosages (7.5 - 10mg). INR-based warfarin dose adjustment calculator. Get suggested weekly/daily dosing, initiation protocols, drug interactions, and clinical guidance. Free tool. Detailed Warfarin dosage information for adults and children. Includes dosages for Myocardial Infarction, Prevention of Thromboembolism in Atrial Fibrillation, Myocardial Infarction - Prophylaxis and more; plus renal, liver and dialysis adjustments.